During the procedure, a small amount of radioactive isotope called myoview is injected into a vein, one injection is given through an iv when you first begin the exam called resting images, and a second injection is given while you exercise on a treadmill. Technetium tc 99m tetrofosmin drug information, professional. Highlights of prescribing information hypotension, throat. Tetrofosmin, a human prescription drug labeled by mediphysics inc. Side effects of myoview technetium tc99m tetrofosmin kit. The myoview radioisotope will be infused through the intravenous approximately 1 minute prior to the end of exercise. If blood flow is limited due to cad, then the amount of myoview into your heart muscle may be reduced. With clinical experience and offering operational flexibility, lexiscan regadenoson injection has been an important part of the nuclear cardiology community for over a decade and counting. Tell your doctor if you are pregnant or plan to become pregnant before using myoview. During the procedure, a small amount of radioactive isotope called myoview is injected into a vein, one injection is given through an iv when you first begin the exam called resting images, and a second injection is given while you exercise on. Ge healthcare to test the radiochemical purity rcp of the radiopharmaceutical uses instant thinlayer chromatography itlc impregnated with silica gel paper itlcsg pall corp. Full prescribing information 1 indications and usage lexiscan regadenoson injection is a pharmacologic stress agent indicated for radionuclide myocardial perfusion imaging mpi in patients unable to undergo adequate exercise stress.
Before myoview can calculate the dimensions of a mounted vessel, the user has to define a region, wherein myoview will track the vessel wall and calculate all the parameters. A reststress protocol using tc99m sestamibi from the pi values for the same. Myoview kit is supplied as a pack of five vials for. You may leave the facility after exercising but will. I was told that for the resting part i received 444 mbq of myoview technetium99m and for the stress part i received another 907 mbq of myoview technetium99m. Lexiscan regadenoson injection for intravenous use. Diagnostic aid, radioactive cardiac disease accepted. Please see adjacent page for brief summary of prescribing information. The myoview kit is supplied as a pack of five vials for use in the preparation of a technetium. Find patient medical information for myoview kit intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Exercise myoview what is a w hat is an exercise you may have. Cardiolite kit for the preparation of technetium tc99m sestamibi for injection, is a myocardial perfusion agent that is indicated for detecting coronary artery disease by localizing myocardial ischemia reversible defects and infarction nonreversible defects, in evaluating myocardial function and developing information for.
See manufacturers package insert for complete instructions 01. Octreoscan package insert pdf indium in 111 decays by electron capture to cadmium111 stable and has a physical halflife of 2. However whenever we read something you can bet there is another study somewhere that will contradict what you read. Myoview stress test if your physician is not satisfied with the results of your ecg and exercise stress test, you may need a myoview scan.
The method suggested in the package insert for 99m tctetrofosmin myoview. The radioisotope, technetium99m, is chelated by two 1,2bisdi2ethoxyethylphosphinoethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin tc99m tetrofosmin is rapidly taken up by myocardial tissue and. I am concerned about my radiation exposure and how this radiation exposure might affect me in the future. Lexiscan regadenoson injection is a pharmacologic stress agent indicated for radionuclide myocardial perfusion imaging mpi in patients unable to undergo adequate exercise stress. Jul 26, 2017 myoview tetrofosmin injection, powder, lyophilized, for solution out of scope out of scope for rxnorm and will not receive rxnorm normal forms. Common myoview side effects a study of fda data ehealthme.
Pdf a rapid radiochemical purity testing method for. Exercise myoview what is a w hat is an exercise you. The package insert states that there is no proven successful management of extravasation after it occurs, although sympathetic block and heparinization are commonly employed during acute management. Technetium tc 99m albumin aggregated injection is a lung imaging agent which may be used as an adjunct in the evaluation of pulmonary perfusion in adults and pediatric patients. Patient information for myoview 230 micrograms kit for.
Myoview kit for the preparation of tc99m tetrofosmin for injection. The reason for the difference may be due to whether the studied subjects ate and had gallbladder contraction. Technetium 99m tc tetrofosmin is a drug used in nuclear medicine cardiac imaging. For stress and rest imaging, two separate doses of myoview are used. The mediphysics myoview kit is supplied as a pack of five vials for use in the. Kit for the preparation of technetium tc99m mebrofenin for. Myoview is a diagnostic radiopharmaceutical for intravenous use only. Find information about common, infrequent and rare side effects of myoview kit intravenous. Highlights of prescribing information these highlights. Technetium tc99m tetrofosmin is a radioactive drug and should be handled with appropriate safety. Mebrofenin for intravenous use, for diagnostic use. Technetium tc 99m tetrofosmin is a radioactive diagnostic agent. A myoview stress test is used to check for coronary artery disease. Physical characteristics indium in111 decays by electron capture to cadmium111 stable and has a physical halflife of 2.
Octreoscan package insert pdf octreoscan package insert pdf download. The standard radiochemical purity rcp testing method for 99mtctetrofosmin as described in the package insert requires extensive time 2030 min and considerable skill to achieve accurate. See full prescribing information for myoview 30 ml. Myoview 30ml kit for the preparation of technetium tc99m tetrofosmin for injection description the myoview 30 ml kit is supplied as a pack of five multidose vials for use in the preparation of a technetium tc99m tetrofosmin intravenous injection to be used for the scintigraphic delineation of regions of reversible myocardial ischemia in the. Highquality imaging done fast as early as 15 minutes postinjection, per package insert 1. Discover lymphoseek, the only agent designed and fdaapproved for lymphatic mapping in patients with solid tumors for which this procedure is a. Aug 29, 2019 myoview may interact with other drugs. Insert a venting needle standard 1826 gauge needle, not provided through the rubber septum of the shielded vial containing the lyophilized powder. Room temperature storage both before and after reconstitution. Aminophylline aminophylline this product information is intended only for residents of the united states.
Technetium99m tetrofosmin myoview is a cationic diphosphine with good. The radiation absorbed dose is similar to that of tc99m sestamibi table 162, although the package insert states that the gallbladder receives the highest dose 5. An alternative method for determining the radiochemical purity of 99mtctetrofosmin article pdf available in journal of nuclear medicine technology 391. In myoview a zone is placed by left clicking and dragging a box across the video image of the vessel in the image analysis control window marked in figure 2. For comparison, identical chromatographic experiments were performed following the method recommended by the manufacturer in the package insert of 99m tctetrofosmin, which uses the solvent mixture of 35. For a listing of dosage forms and brand names by country availability, see dosage forms sections. A small amount of a radioactive substance is injected into your bloodstream at peak exercise. The myoview is carried by the blood to the heart muscle.
I have read that myoview stress test with a scan before and after the exercise portion is more accurate than the standard exercise test. Pdf a rapid radiochemical purity testing method for 99mtc. Draximage maa kit for the preparation of technetium tc 99m albumin aggregated injection indications. Tetrofosmin tc 99m an overview sciencedirect topics. The products dosage form is injection, powder, lyophilized, for solution, and is administered via intravenous form. Synthesis of the myoview tm ligand, bisphosphinoethane 1,2c14tetrofosmin article pdf available in journal of labelled compounds 5056. Myoview tetrofosmin injection, powder, lyophilized, for solution to receive this label rss feed copy the url below and paste it into your rss reader application. Imaging guidelines for nuclear cardiology procedures. Myocardial technetium99mtetrofosmin and technetium99m. The mechanisms for uptake and retention of technetium tc 99m tetrofosmin by myocardial tissue are not well established 01. Aug 29, 2019 the myoview and thallium201 images were separated by a mean of 5.
Experience the potential benefits of myoview for healthcare providers. Yes how many people have myoview side effects are studied. Lower dose range helps minimize patient radiation exposure. Myoview 230 micrograms kit for radiopharmaceutical preparation. The myoview 30 ml kit is supplied as a pack of five multidose vials for use in the preparation. This is based on results in animals with other known arteriolar irritants. Insert the syringe needle into the vial through the center of the stopper and direct the stream of sterile water for injection to the glass wall of the vial to avoid excessive foaming. The ndc code 1715602630 is assigned to myoview also known as. Sestamibitc99m prescribing information package insert. Myoview kit for the preparation of technetium tc99m fda. Our myoview kit for the preparation of technetium tc99m tetrofosmin injection for intravenous use side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
An alternative method for determining the radiochemical. A rapid radiochemical purity testing method for 99mtc. Adenosine induces direct coronary arteriolar vasodilation through speci. Package insert states that injection should be administered within 8 hours after preparation since it does not contain a preservative 01 04 06. The practitioner should be familiar with the package insert for each medication.
Gently swirl the vial for at least 15 seconds to dissolve the lyophilized powder. Tell your doctor all medications and supplements you use. Technetium tc 99m tetrofosmin is a lipophilic cationic agent diphosphine group 01 02 04 09 14. Product is stable 90% radiochemical purity is maintained for 8 hours after reconstitution 04. For myoview imaging, each subject received 185296 mbq 58 mci tc99m tetrofosmin at peak exercise and 555888 mbq 15 24 mci tc99m tetrofosmin at rest approximately 4 hours later. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food. Current and future risks from a myoview stress test. Myoview kit for the preparation of technetium tc99m tetrofosmin injection for intravenous use. The myocardial uptake of technetium tc 99m tetrofosmin appears to occur by a passive diffusion process. Myoview tetrofosmin injection, powder, lyophilized, for solution mediphysics inc. Myoview is a kit for the preparation of technetium tc99m tetrofosmin injection for intravenous use. The recommended dose range for myoview for ventricular function assessment is 1851221 mbq 533 mci as a intravenous injection 2.
It is sold under the brand name myoview ge healthcare. Please consult full prescribing information before using. The radioisotope, technetium99m, is chelated by two 1,2bisdi2ethoxyethylphosphinoethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. Myoview is indicated for assessment of left ventricular function left ventricular ejection fraction and wall motion in patients with known or suspected heart disease. When rest and stress injections are administered on the same day, the first dose should be 5 12 mci and followed by the second dose of 15 33 mci given approximately 1 4 hours later. Kit for the preparation of technetium tc 99m sestamibi.